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Iris and eye color

How was born the eye color?

 

The iris is the diaphragm of the eye. It gives color to the eyes; (Brown) Brown, green or blue. The iris is one of the components of the uveal tissue of the eye (uvea), which also includes the ciliary body and the choroid. Many questions exist as to the color eyes, and the possibilities of change. It is important to know some of the characteristics of the anatomical support of the color of the eyes: the iris.

Iris geometry

The geometry of the iris is a circular opening called perforated disc pupille. The pupil diameter varies from 1 mm (conditions conditions of high brightness, tell photopiques, which cause a constriction of the pupil called myosis) and 9 mm (conditions conditions of low brightness, tell scotopiques, which cause dilatation of the pupil - Mydriasis). The eyes which the pupil is wide and which are taken picture Flash may appear red on the shots. Of course, this color is not related to the color of the iris but the backscatter of the illumination of the back of the eye by a richly vascularized tissue (retina).
The diameter of the iris is close to 12 mm. Its thickness varies, it reaches 1.5 mm at the iris flange, which is the thickest area and located about 1.5 mm from the pupillary edge. The base or root of the iris does in comparison only 0.5 mm thick. The pupillary edge of the iris rests on the anterior side of the Crystalline lens. The iris forms a tablecloth comparable to that of a truncated cone, as the pupillary edge is located in a plane slightly more anterior than its root (due to the vaulted of the Crystalline lens).
The iris represents the boundary between the anterior chamber and the posterior chamber of the eye. Thus, the so-called "anterior chamber" implants are inserted and placed in front of the iris. The so-called "posterior chamber" implants are inserted in the rear of the iris against the Crystalline lens.

Only the front of the iris is accessible to the review, and it is this face that gives color to the eyes.

Example of iris (perceived as) Blue: this color is due to the lack of pigmentation of the anterior layer of the iris. Blue eyes do not have an iris blue (in the sense where it contains no blue pigment), but this color is linked to the preferential dissemination of the short wavelengths of the visible spectrum (just as the atmosphere preferentially diffuse blue which is the color of the sky). The local color of the iris weakly or not pigmented variations on its front are so induced by how irien fabric broadcasts reflecting incident light, which is usually polychromatic light natural (Sun) or artificial (bulbs). That is why the perceived as blue iris often have related variations of intensity or blue, or

Example of iris (perceived as) Blue: this color is due to the lack of pigmentation of the anterior layer of the iris. Local variations of the color of the iris are induced by the way irien fabric diffuse reflecting incident light. When the color comes to the gray, broadcasting for a spectrum of wavelength larger than for steady blue (see below).

Histology of the iris

From before backward, there are several layers.

Histological description simplified IRIS. The anterior layer is formed of a collagen matrix where is tangled fibroblasts, and pigment cells (melanocytes) located a little more in depth. Brown, Hazel and green eyes have a variable proportion of these cells, which lack the blue eyes.

Histological description simplified IRIS. The anterior layer is formed of a collagen matrix where is tangled fibroblasts, and pigment cells (melanocytes) located a little more in depth. Brown, Hazel and green eyes have a variable proportion of these cells, which lack the blue eyes.

The anterior layer of the iris

This thin layer is an extension of the stromal layer: it is the most superficial, and it is what gives its appearance and color in the iris. It is composed of various cells: fibroblasts (who make collagen), of melanocytes (which contain the pigment). These cells are inserted into a frame of collagen fibrils. Collagen fibers have a rather radiaire orientation. Fibroblasts have a particular form: these cells form many interconnections, which are partly responsible for the fine variations of corneal relief (with an alternation of small ledges and hollows or Crypts), and which are distributed of random material. These structures play also a role in color like the IRIS, because they cause the visible light diffusion, more marked in the short wavelengths (blue). The density of the network formed by the expansions of the fibroblasts varies from one eye to the other.
Under the most superficial layer of fibroblasts, the melanoma cells are located. When clustered, they form small, pigmented ridges comparable to Neavi.

The iris and her sphincter stromal layer

The stromal layer consists of collagen tissue of pigmented and non pigmented cells. At the level of the peripheral flange, the arterial circle of iris is a vascular structure where to leave the arteries of the iris, that have a radiaire trip directed to the pupillary edge.
The sphincter of the iris is a smooth muscle, whose width is about 1mm, and which is responsible for the constricting movements of the iris (reduction of the diameter of the pupil: The sphincter allows the miosis). The sphincter is innervate by parasympathetic fibers.
anterior epithelium and dilator muscle
A The deeper part of the iris is the anterior epithelium, which is composed largely of Myo epithelial cells, whose expansions directed to the Stroma form the iris dilator muscle. Because of their radial orientation, the contraction of this muscle causes a dilation of the iris (sympathetic innervation). Some eye drops stimulate the contraction of these fibers, and allow to dilate the pupil. Some of these eye drops are called "cycloplégiques" eye drops. They are used for the examination of the background, and also to paralyse the accommodation (study of the refraction Cycloplegic, which is often realized during the balance of refractive surgery).

The posterior epithelium

The posterior irien epithelium consists of a single layer of pigmented cells. The pigmentation of these cells decreases on the periphery of the iris, and this layer becomes the epithelial layer of the ciliary body. The pigmented, the deepest layer is the one that can leave its mark on the surface of the lens, when hugs repeated with the anterior side of the lens (we call these hugs of the cervix).

Color of the iris

Before studying the factors that influence the color of the iris (eyes) more specifically, it is important to remember some important information concerning the notion of colorful sensation. The color of a light perceived by the eye (or rather the brain) depends on the wavelengths that composes (nt). The color of an object depends on the light it emits or reflects and who is captured by the eye of one who observes it. The color of an object is in fact influenced by the light that "enlightens".

Under normal conditions, the light that illuminates our terrestrial environment is sunlight, which contains all of the radiations of light visible (the mixture of these radiations causes a feeling of 'white' light). Plucked from an Apple tree, an Apple is green for located in its skin pigments absorb all of the radiation colored solar light which illuminates it... except the radiation seen as green. This absorption is related to the interaction between photons and electrons of the constituent atoms of the pigments concerned and located in the skin of the fruit. Green radiation are reflected in a diffuse way in all directions. If it illuminates the same Apple by a red light, it will appear almost black, because all the incident light (red) will be absorbed by the pigments: it would be the same with a Red Apple illuminated by a green light.

Regardless of the amount of light it absorbs and reflects in a diffuse way, the color of the iris of the eye depends primarily on the type of the light it receives. It is for this reason that the eyes, regardless of their "base" color in natural light, are undergoing changes of tone depending on the light environments (whether natural or artificial, light etc.).

A dark object (piece of coal) absorbs almost all the incident light, while a white object reflects in a diffuse way without preferential absorption (ex: snow). The melanocytes of the human skin absorb ultraviolet and an important part of the visible spectrum. They darken the skin because it, absorbing more light, reflects less.
An object that lets or reflects light by diffusing it (scattering in all directions) can have an effect on the colour perception, if it diffuses the light more or less selectively towards the wavelength. Depending on the size of the particles that diffuse the light to that of the wavelengths considered, some coloured radiation will be more diffused (deviating from their path) than others: the smaller the object is to the length And the less it affects the path of the incident ray and vice versa.

For a light of 'normal' composition (ex: natural light), the color of the iris is influenced by several factors:
– The structure and density of collagen fibers of the anterior stroma and the anterior layer
– Density in melanoma cells (pigmented cells)
– The density of pigments contained in melanoma cells
Schematically:
– The higher the number of melanoma cells, the more pigment they contain, the more brown and dark the iris appears; In fact, the incident light is absorbed by these structures, which reflect it little, and thus appear dark.
– Blue eyes have an anterior layer devoid in pigmented cells : light is not absorbed, and she is thoughtful and broadcast more significantly by structures which the microscopic dimensions make the short wavelengths (blue) are more distributed than the long (known as Rayleigh scattering: Blue is broadcast about 16 times more than red). This type of scattering also explains the color of the sky: the molecules and atoms present in the atmosphere more diffuse radiation of wavelengths blue wavelengths than red. Thus, blue light is more diffused in all directions, toward the ground, as the light of wavelengths higher and (red). When you look up to the sky, in proportion received more bluish radiation, and the sky seems blue. The Sun appears yellow because the rays of light reaching the eye are "depleted" blue (by higher diffusion towards the longer radiation). Clouds are white because they broadcast in a non-preferential manner all visible colors.
– Earlier iriennes structures also preferentially diffuse blue light: In the absence of marked absorption (not or little melanocytes), it is a light more intense and "enriched" in blue (relatively) which returns to the eye of The Observer.

Blue Iris by diffusion
– The green eyes are fitted with medium-pigmented irises, which absorb some of the incident light. The mixture between reflected and diffused light and partial absorption leads to a colorful perception of clear to green hazelnut.
Color variations within the same iris are explained by variations in the scale of enabling structures, fluctuations in density of pigmented cells, etc.

The light that is not absorbed by the earlier iris or diffused layer in reflection goes more in depth is absorbed by pigmented posterior epithelium cells. Albino eyes, whose color is gray to bluish, are devoid of pigmentation not only at the front of the iris (anterior layer) but also to his back. The albino patients are photophobes, because light entering the eye is too important.

 

Changes in eye color

Many patients express the wish to change forever eye color: in the overwhelming majority of the case, it's patients to brown eyes, wishing to have blue eyes.

Laying of prostheses of iris, in front of the natural iris which is then hidden, to change the color of the eyes in a spectacular way. Implants of artificial iris have been proposed and put (a technique recently proposed and called "Bright ocular" is based on this approach).

The illusion is quite successful, even if short distance (or slit lamp examination), the appearance of the prosthesis greatly differs from the front of the iris. In addition, the diameter of the pupil (artificial since formed by a hole about 4 mm in the center of the prosthesis) is fixed. This reduces the expression in the eyes that appear more frozen, especially in low light conditions.

IRIS blue bright ocular

Prosthesis artificial iris to change the color initially Brown eyes. At a faible low distance or after magnification, texture and the pattern greatly differs from that of an iris naturally blue (implant 'ice gray'). Here, the prosthesis is tinged in blue (it absorbs all the colors of the visible spectrum except blue), which are naturally blue eyes have a little pigmented iris which induces the broadcast increased blue light.

The comparison between a review of pupillometry performed before and after the placement of implants of iris shows the fixity of the diameter of the artificial pupil of the iris prosthesis:

Implant iris pupillometry

Pupillometry performed before and after implant of iris (the images are in black and white). Iris implant has a central hole whose diameter is 4 mm. Before the intervention, the natural pupil dilates in the half-light (examination mesopiques conditions). After the installation of artificial iris in front of the natural iris, the pupillary game is no longer visible. Bottom left, we guess a fringe of natural iris, the centering of the artificial pupil being slightly offset with respect to the natural pupil (arrow)

In a significant number of documented case, this site has Ocxxx_xxx_5163ionne of the irreparable damage (severe glaucoma inducing a legal blindness in some case). Other complications, which seem inevitable after a certain delay, associate chronic Uveitis (friction between the iris and the implant), and the loss of endothelial cells (cells at the posterior face of the cornea).

Unfortunately, he is no reliable, effective and devoid of risk technique to change the eye color of a permanent and definitive.

 

Studies on the use of impacts of Yag laser on the anterior layer of the iris are underway; These impacts cause inflammation of this layer superficuelle, and cellular phenomena involving the action of macrophages recruited (and then ingesting the melanin and pigment cells). The effects of this technique seem limited on the cosmetic front, iris taking that rather grayish blue next to the box of the impacts. Its effectiveness, but also its safety remain to demonstrate.

It is of course possible to wear contact lenses 'of color' to get, the time of day, the eyes of a different color. Recall that color lenses, as correction lenses (there are also colorful correction lenses) are devices that should be taken as under medical control and contactologique, and by rules d' use and very strict maintenance.

The cosmetic result of these processes is often considered disappointing: the "blue" color of the eyes is not necessarily easy to reproduce, since the optical mechanism originally this bluish coloration (diffraction and not selective pigmentation).

Some eye conditions cause a change of the color of the iris: the follows of Fuchs is responsible, on the side of the achievement, a clarification of the color of the iris, due to the gradual disappearance of the pigmented cells. One speaks then of IRIS heterochromia.

IRIS heterochromia, wall eyes

Example of IRIS heterochromia: in this example, both eyes were originally of the same hue (that of the right eye of the patient). This color was green with a Browner color to the pupil (due to an increasing proportion of melanocytes of the previous slip of the iris pigment to the pupillary edge). A pathology called follows (or Uveitis) Fuchs appeared: this disease whose exact origin is unknown is characterized by the presence of an inflammation of the eye, specifically the uveal tissue. Prolonged inflammation is responsible for a gradual disappearance of melanocytes and irien pigment. Iris then takes a blue tint.

The heterochromia can be congenital, as in the following example:

"Wall" eyes, congenital heterochromia.

'Wall' eyes, congenital heterochromia.

 

 

 

Eye drops containing prostaglandins or derivatives, used to reduce intra ocular pressure in patients with glaucoma (ex: latanoprost) cause increased IRIS pigmentation, and can thus make less blue eyed (green or brown). This pigmentation is final. It is preferable to use another class of eye drops anti glaucomatous patients to the blue iris, who want to retain this coloration.

In eye surgery, especially cataract, a lesion of the iris may cause a local discoloration of the iris.

Permanent changes in the diameter of the pupil can also give an impression of changing the color of the affected eye. A famous example is that of the late English artist David Bowie, whose eyes were not truly minnows; victim of local trauma in childhood, the pupil of the left eye of Bowie remained in Mydriasis (Permanent dilation), which darkened the aspect of this eye to the dilated pupil, towards the other eye to clear iris. This feature gave the illusion of wall eyes, and a feeling of particular strangeness related to the more or less subliminal perception of a difference in pupil size (anisocoria).

Finally, remember that surgery refractive corneennne (LASI, PKR, etc) will cause no change to the color of the eyes.

63 responses to "Iris and eye color"

  1. ALMAS Tulay says:

    Hello I would like to know the city where you do the colored iris implant
    Know the price of the intervention
    How many times do I have to do this?

  2. Dr. Damien Gatinel says:

    Must be repeated again and again that the insertion of implants of colorful iris operation is an OPERATION that should not realize because it EXPOSES A fatal COMPLICATIONS (glaucoma, cataract, endothelial decompensation of the cornea, chronic uveitis, etc.).

  3. Carine says:

    Hello, I have blue-green eyes and I discovered that the perimeter of my iris color had changed. It became Brown and thick in its lower part; the same dark pretending Brown gradually spill over the iris. I feel helpless because I can't find anything to enlighten me.
    Thank you

  4. Dr. Damien Gatinel says:

    It may be a lesion of the iris as a Nevus, and I advise you to do a consultation without emergency with your ophthalmologist.

  5. Catherine domain says:

    My dark brown eyes are becoming green. H' have 75 years is there is a pathology related to this change? should I consult? I'm a librarian and I'm still working and I need my eyes! Thanks in advance for your answer

  6. Dr. Damien Gatinel says:

    This color change is most certainly the to depigmentation of the previous slip of the iris. A slightly brown iris, which is dépigmente has a color more clear, then green and finally blue in case of total depigmentation. This change is certainly trivial, if it is bilateral and very gradual.

  7. Sabrine Ghezal says:

    Hello doctor damien practise you the color change? and if yes how much costs. response thank you

  8. Dr. Damien Gatinel says:

    There is no safe and effective technique to change the color of the eyes. The implants are dangerous because it causes irreversible damage to the cornea, inflammation and flare-ups of tensions in the eye, and we received many patients operated with these implants it took to remove emergency. This is why I do not practice this intervention, which to my knowledge is made nowhere else in France for security reasons.

  9. Noemy says:

    Hello doctor do you practice the laser eye color change?

  10. Dr. Damien Gatinel says:

    I was approached by the American society Stroma Medical to start a study clinical in France, and which should take place in 2017 to the Rothschild Foundation. Some patients benefit from a treatment designed to clear up the iris, or even change the color of it. According to this company, a laser (YAG in green light) is delive on the surface of the iris in several sequences of a few seconds each. This causes an inflammatory reaction, the activation of macrophages, and digestion of the melanocytes (pigment cells) of the previous slip of the iris. In theory, if these cells disappear, the color of the iris may become blue. Clinical studies conducted so far have exposed only a small surface of the iris to the laser, and we see in the photographs provided by Stroma that this surface dépigmente relatively evenly. The effect appears gradually, in a few weeks. It remains to check the safety of this procedure, and the terms of its realization. Preliminary clinical studies are planned to the Philipinnes in near future.

  11. ME says:

    Hello doctor,

    If the clinical trial begins in 2017, it takes usually how long before practice?
    Indeed I have my daughter who has a HBC and it turns out that she has an iris clearer than the other and suddenly I wanted to know if one day she could lighten the darker iris of the two or the inverse

  12. Edward says:

    Can without eye black to clear Brown eyes or noisttes with a laser?

  13. Edward says:

    Is possible to go from black eyes to clear Brown eyes by laser or is it's just when you have brown eyes and you want blue eyes?

  14. James Brown says:

    My problem is this combined operation trabulectomie cataract in both eyes followed an inflammatory phenomenon +++. I have brown eyes. Today I present a pigmentation of the implant on the right which blocked particularly reduced vision. What is the origin of this pigmentation and what can be done?
    Joëlle

  15. Dr. Damien Gatinel says:

    The pigment comes initially from the posterior leaflet of the iris (which does not give the color of eyes, unlike the previous sheet) and is always pigmented (except case of albinism). case complication chirurigale, a drop of pigment can occur, but to do specify the cause to your surgeon.

  16. Dr. Damien Gatinel says:

    Initially the two variations are possible. The 'black' eyes are actually dark 'brown' eyes, and if the laser keeps his promise, he might actually be able to lighten very pigmented eyes, and make your Brown eyes blue. It is necessary to check that this concept gives predictivles results and safe, what should be done in the coming months. The Rothschild Foundation should be the first (or European) french Center the company Stroma Medical laser equupe

  17. Dr. Damien Gatinel says:

    This is part of claimed by the company Stroma Medical possibilities. Currently, preliminary studies helped locally dépigmenter Brown irises. The treatment was limited to an area (located under the upper eyelid). Photos that I could look at show a fairly important depigmentation. I could not yet visually observe the result of a "complete" laser 360 treatment.

  18. Dr. Damien Gatinel says:

    A priori it is easier to clear up an iris of him go... But the full clinical feasibility of the depigmentation of the previous slip of the iris laser is still showing. Clinical studies are evidence-based, it is estimated that the start-up of the routine treatments can take place in the aftermath, so current 2018 if everything goes well.

  19. Aude F. L. says:

    Thank you Dr for these valuable explanations. In Spain in Barcelona, within the clinic "NewEyes Laser" a man named Dr. Pedro Grimaldos Ruiz practical laser for dépigmenter the iris using the laser. Do you understand you that this operation is allowed within the European Union? the fact that she be allowed in Spain certainly means that she will also be in France...

  20. Dr. Damien Gatinel says:

    This is to my knowledge of a personal initiative, with hijacking of a laser that is not intended to dépigmenter the iris to try to do.
    It is a priori very advisable to embark on this procedure with a laser not studied for this, because the risk of lesions of ocular structures is important. The laser currently developed by Stroma is specifically designed to be focused in the iris plane, with motion detection system, and pupil protection (to avoid damaging the Crystalline lens and retina). It is not because a practitioner develops a technique that it is "allowed". The official authorisation procedures are long and complex and cannot be done without the assistance of the company that develops an instrument. We need to fill out a very detailed file, provide the results of clinical studies, etc. This usually takes months or even years, especially for medical devices deemed "invasive", as is a priori any system of radiation delivery with intra-ocular action.

  21. Damien Emeyriat says:

    Hello doctor,

    We cannot yet change eyes 'black' in colors other than blue? I would like to get a honey color but only implants or ocular lenses appear to exist to achieve this result... Do you know a practitioner able to do this is it you please?

  22. Dr. Damien Gatinel says:

    Repeat again and again that to date there is no operation that allows to change the color of the eyes without risk. Essays about a laser (Stroma) may occur in the near future. Depigmentation of the previous slip of the iris should cause a clarification of it, but a "honey" color is not the priori program...

  23. Guy.B says:

    Hello doctor,

    I have the outline of the iris of my eyes that happened in recent years, Brown to light blue.
    What do you recommend?

    Thank you

  24. Carole says:

    Hello, if one day the Stroma laser becomes operational to brighten the eyes, cannot t - you then get blue (thus removing all of the pigment from the iris) or will t - they modulate by removing for example that a little pigment?
    So a person with green brown eyes wanting to lighten his eyes slightly to make them greener, can you get the desired result? Or can it only get you blue?
    Thanks in advance

  25. Dr. Damien Gatinel says:

    It's a pertinent question. One of the question marks raised by this technology (at the stage of preliminary clinical trials), is the degree of "depigmentation" obtained after a standard session. Theoretically, one could actually consider that a partial depigmentation modulates the color of brown to green. It will certainly take time to refine this technique, if it works well enough and is not dangerous for the eye tissue, what the first trials will need to demonstrate.

  26. Dr. Damien Gatinel says:

    It may be the occurrence of a "gerontoxon", which translated the occurrence of deposits on the periphery of the cornea: is often seen this in patients who have abnormally high levels of cholesterol.

  27. Galliot says:

    Hello doctor, I sex question which bothers me since always. On one of my two eyes, color (which is brown) of my iris overflows on the white part of my eye (as if the color would"casting"). I have no problem, but I wonder where it came from. Thank you for your response.

  28. Dr. Damien Gatinel says:

    It is possible that this pigmented task corresponds to a "Nevus" 'Mole' of the conjunctiva. An ophthalmologist can confirm you this.

  29. Mark says:

    Hello doctor,
    What do you think of the keratopigmentation to change the color of my eyes?
    I am tempted in view of the results...
    Is it risky?
    I specify that I have very dark brown eyes.
    Thank you.
    Yamina

  30. Dr. Damien Gatinel says:

    The keratopigmentation is to insert the pigment in the cornea, it is a techique little or not reversible and is not really committed to my knowledge to this day.

  31. Danielle says:

    Cataracts affect the color of the iris? My ophthalmologist has diagnosed me with a beginning of cataracts and a friend to whom I was talking told me she had just noticed that my blue eyes were less glittering than before, that my look was more off...
    If so, would an operation for cataracts make me look like before?
    Thank you for answering me

  32. Dr. Damien Gatinel says:

    Priori cataract has no particular effect on perceived IRIS color. Cataract is a clouding of the lens, and the latter is behind the iris. Advanced cataracts can cause yellowing (then a whitening in very advanced forms) of the pupil, but again there is little likely that your eyes (in all case regarding the color of the iris) has been changed by a beginner cataract.

  33. Veyrat says:

    Hello my mother-in-law to a beginning of dementia and parkinson's disease. A few days ago I noticed that his light brown eyes had clarified to the point of being blue or bright grey. Then she got sick, certainly an epileptic seizure, stayed 10 days in the Hospital where she was treated and more for a urinary tract infection. Since his eyes returned to the light brown. I asked her doctor but there is no answer to this very quick clarification. Could you tell me more?

  34. Dr. Damien Gatinel says:

    It is probably a subjective impression, may be related to changes in pupillary diameter. It is unlikely (very unlikely) that the iris has actually changed color. With age, the iris tend to be dépigmenter, but it is a slow and irreversible process.

  35. Mardesic says:

    Hello
    I'd like to do this operation!!! I facinée with clear eyes! This is my most expensive wish but how to make

  36. Dr. Damien Gatinel says:

    Unfortunately, no technique is possible to date, iriss implants are very dangerous and should not be placed under pain of eye complications in more or less long term.

  37. Bouhkadra says:

    Hello Dr,

    Do you have any news regarding the marketing of the stroma laser please?

    Kind regards

    Sabine

  38. Dr. Damien Gatinel says:

    This is postponed from year to year because the studies that were to be carried out (Philippines) have not yet been initiated (to my knowledge, last point in May). The reasons for these delays are not disclosed, but it seems that they are related to technical concerns at the level of the laser itself. We must therefore remain very cautious, because despite commercial announcements, no human iris had been treated in full (in May 2017). The expected results are purely speculative, and disappointments are not to be excluded. Let us repeat again that there is no method of changing the color of the eyes in a perennial way in ophthalmologic surgery. iriss implants are to be avoided absolutely because of the serious complications they cause invariably. The laser to lighten the eyes is at a stage of development still beginner.

  39. Delphine says:

    Hello doctor,
    The iris of my right eye, usually green, changed color: Half the iris, on a very sharp diagonal became brown.
    I have had several seizures of toxoplasmosis in the right eye (focus on the macula), and for a long time my vision is very disturbed, I can not distinguish whether the acuity has fallen since.
    Is this a natural change or should I consult? Thank you

  40. Dr. Damien Gatinel says:

    I invite you to consult because it is not normal a priori that the iris become brown. This may be a "nevus" type lesion ("mole" which may develop on the front side of the iris that contains melanocytic cells). A ophthalmologist will be able to explain the reason for this change.

  41. . says:

    Is it possible to change the eye color to have minnow eyes?
    Thanks in advance

  42. Dr. Damien Gatinel says:

    To date, there is no safe technique to change the color of the eyes. Iriens implants represent a certain danger. There is a hope regarding the technique developed (laser to change the color of the iris – Stroma Company), but this treatment is not yet available routinely, clinical trials are underway in some countries.

  43. Valérian says:

    Hello doctor,
    My eyes change colors during the day, (it varies between blue and green) This change can be done by nuance but also brutally (it happened to me in the same evening to move from the blue nuanced green has a very intense green).
    Do you have an explanation? Do I have to worry about that? I already smoke in the past cannabis and the effect is direct blue-> green Why?

    Thanks in advance
    Kind regards

  44. Bouhkadra says:

    Good evening, doctor.

    Do you know if the laser will be available soon?
    Thank you

    Kind regards

    Sabrina

  45. Dr. Damien Gatinel says:

    The company Stroma, which intends to commercialize a laser designed to lighten the eye color, continues its pre-clinical studies and should communicate on its website when the laser is available.

  46. Dr. Damien Gatinel says:

    The apparent color of the eyes is under the influence of many parameters. Even brown eyes may appear more or less clear depending on the light they receive (and return) and the diameter of the pupil. The same goes for the clearer iris.

  47. Larry Marionnaud says:

    Hello doctor, what do you think of the honey (diluted) to lighten the eyes gradually please? Is this method safe? Thank you

  48. Dr. Damien Gatinel says:

    I do not know if this method is safe (it is not if honey is applied to the eye level!) but it is certainly totally inneficace.

  49. Bouhkadra says:

    Hello doctor,

    My questions concern the laser that changes the color of the eyes.

    The latter may depigmentate the anterior layer of the iris, but can it remove the pigmented cells from the stromal layer?

    If this is not possible, will the eyes remain dark despite superficial depigmentation?

    Thank you for your help

    Sabine

  50. gaschet says:

    Hello

    I have a anisicorie diagnotiquée pupil of Adie for 3 years.
    I have hazelnut-colored eyes

    is t_il a cosmetic solution to mask this anisocoria and also reduce the sensitivity to brightness?

    The colorful iris implant can it be the solution despite the eventual dangers you touch?

    Thank you

  51. Dr. Damien Gatinel says:

    Sometimes there is the possibility of performing a surgical "pupilloplastie", or tattooing the cornea, or even wearing a colorful Contact lens... Iriens implants are not a solution in your situation.

  52. Lena says:

    Hello doctor,
    Is the stroma laser for changing eye color still topical?
    Would you practice it in the future (if it comes out) in France?
    I have been diligently this company since 2009, and hope it will Vera the day soon.
    Good to you.

  53. Dr. Damien Gatinel says:

    Preliminary clinical trials are currently underway, the results will certainly be presented by the company in due time.

  54. Sasha says:

    Hello doctor
    I present a cataract start with both eyes. According to my ophthalmologist, there is no urgency for the operation but I would like to know; If I delay too much for this operation, will the iris or the pupil of my eyes risk discoloring or bleaching.
    Thank you for your answer

  55. Julie lapointe says:

    Hello, I recently consulted my optometrist for a routine exam and also because I felt the diffilculter with the brightness. She finds that pigments of my iris of each eye are detachais and that they stick to my cornea. Could you tell me how it is called and I wonder about whether it is correctable and or regenerative in the long run? Thanks in advance

  56. Dr. Damien Gatinel says:

    This is certainly the so-called Rétrocornéens precipitates pigmented. In some case, when pronounced, they may correspond to "bundles of Krukenberg", and in addition, the deposit of pigment iris in certain ocular structures such as Trabeculum ( Where the intraocular fluid is absorbed) may hinder the smooth flow of fluids and increase intraocular pressure. It is then spoken in certain proven forms, with altered visual field of "pigment glaucoma". It is important that you are able to consult an ophthalmologist to make a more precise point about these pigments (there are other causes that can cause the presence of these).

  57. Dr. Damien Gatinel says:

    No there is no risk of discoloration of the iris with the cataract.

  58. Elon Stark says:

    Hello doctor,
    Any news on the stroma laser?
    Thanks in advance

  59. Dr. Damien Gatinel says:

    No news as far as I'm concerned, I haven't had any direct contact with this company for about 2 years, the least we can say is that you have to be patient.

  60. Desacy says:

    Hello Mr Gâtinel, I understand that you had no news compared to the laser stroma could you tell me however if it is possible from your own means and the current technology in France to be able to do slightly Lighten the brown eyes so that they have light brown or slightly green I will be very happy to be able to participate in this intervention if however you could and of course be in your hands, I have no financial means but ready to Try the experience thank you for your reply in advance, well cordially.

  61. Dr. Damien Gatinel says:

    There is currently no reliable and available technique for even light clarification of eye iris.

  62. PATHIYATTIL says:

    Hello doctor,

    Following an accident (I received a hook in the left eye) the irinian sphincter was broken. Since that shot in the eye I see less well.

    Is there an operation to repair this muscle?

    Thanks for your reply.

  63. Dr. Damien Gatinel says:

    It is sometimes possible to make a suture of the IRIS (pupilloplasty), depending on the context and the local State.

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