The PEARL-DGS formula, developed by Debellemanière, Gatinel and Saad and published open-source, computes IOL power by combining thick-lens equations with machine-learning models that predict the posterior corneal radius and the effective lens position (TILP). The tool offers three dedicated modules: « Regular Eyes » for standard cataracts (choice of keratometric index, biometer and IOL model), « Complex Eyes » for challenging cases (corneas after myopic or hyperopic LASIK/PRK, radial keratotomy, scarred corneas, eyes carrying an ICL) and « Second Eyes », which refines the second-eye prediction from the first-eye data. Optional parameters (lens thickness LT, central corneal thickness CCT, white-to-white WTW) further improve accuracy when available.
Key features
- Machine-learning prediction of the lens position (TILP)
- Algorithms suited to corneas after refractive surgery
- Options for radial keratotomy and scarred corneas
- Specific adjustments for eyes carrying an ICL
- Second-eye optimisation from the first-eye data
- Open-source methodology and online access (iolsolver.com)